despode 

A weird sexual position when two people dress up like beethoven and play eachother like instruments for sexual pleasure

Me and my husband despode eachother to death last night

despode by Dickinmyasshole November 10, 2017

Despondex 

Made by Pfizer in collaboration with The Onion News Network, Despondex is the first drug designed to treat the symptoms of excessive perkiness. It can prevent loud joyful squeals when a friend calls, Christmas caroling, costume parties, talking in line at a grocery store, community potlucks, excessive hugging, and smiles.

Are you annoyingly happy?
Despondex could be right for you.
If you are in a good mood occasionally that is normal but if you have a persistant positive outlook on life you should ask your doctor about Despondex.
Now you too can waste a night sitting on the couch with your friends or family watching a TV show no one enjoys.
Despondex prevents happiness better than watching the news, considering man's impact on nature, checking your bank balance, and thinking about how old you are and how little you have accomplished.

Despondex by ericri September 10, 2009

Despondent 

down in the dumps

Fayaz is despondent when Anthony misses their 3:30 PM hug appointment. See also: inconsolable.

Despondent by BrandonWalsh April 11, 2014

Despoedespmnobes 

Good; being of good quality.

That was a despoedespmnobes piece of fish.

Despoedespmnobes by Mr. Rainbow Sunshine February 25, 2009

despondent 

Fucking hopeless.

Johnny was despondent because his IQ was 4.

despondent by Fred Jung. October 17, 2003

despiderfy 

To make a spider go away

I'm gonna despiderfy this room

despiderfy by Bananas_in_pyjamas_are_running August 5, 2021

Despondent 

A state of depression. Unblissful.

despondent, distracted, your vicious, and romantic

Despondent by zZz_Jinxy_zZz January 15, 2007