The inevitable uphill battle you wage against a toilet after eating a large meal at Buffalo Wild Wings. Occurs within 24 hours after eating large amounts of wings and involves loud farts and explosive chicken wing shaped diarrhea.
Joe: "Almost missed my train into the city just now cause I got struck with a brutal, ass-tearing round 2 of the Buffalo Wild Shits. No Sunday picnic, let me tell ya"."
John: "No kidding, I got them on the way to work this morning. Had to book it to a stall and the Buffalo Wild Shits made my bottom burn like mango habañero.
Fingering or giving a hand job to someone by putting your hand down the back of their pants while they are sitting, far enough to where the hand extends to or beyond the crotch on the other side.
While sitting in the stands at the Bills game, I gave my girl a Buffalo Hand Warmer, because we're classy like that.
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.