Refers to the mash up the names of Santana and Brittany from Glee. Usually used by those who 'ship' or support a romantic relationship between the two characters. made famous (ish) by actress Naya Rivera who plays Santana when she used it at Comic-Con 2010. Also known as Brittana...
Girl 1: Oh My Gosh I hope Brittana happens this season on Glee, their characters are so meant to be together.
Girl 2: Oh haven't you heard? We're saying Santittany now since Naya Rivera referred to them as that.
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.