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Negative or derogatory term for a female from Oakland, CA. However, like the term, "nigga", it can be used as a term of friendship, recognition or camaraderie, if used between females on good terms, to denote the fact that they are from the same hometown.
"That bitch is just a stupid O-Ho' who think she knows what's shit. She aint never even bin' across the damn bridge!"

"Oh-my-god-girl! Look at you! What's my O-Ho doin' here in New York?!"
O-Ho' by NO'HC January 12, 2009
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box-o-ho 

a large box, most likely containing a refrigerator or washing machine at one point, occupied by 2 or more prostitutes at any given time.
"Dude, i only had to pay 5 bucks to get into that box-o-ho by the 7-11!"

"Yo momma lives in a box-o-ho!"

cock puffs O'hoolahan 

Famous Dubliner who fiendishly puffs the cock.
Like Jason mewes (Jay and Silent Bob) would say......He (Cock puffs O'hoolahan) LOVES the cock!!
An Irish surname, original form being ohEaghra. Many other variations of this name are Hara, O'Hara etc.

It can also be quite amusing when people are afraid to actually say O'Hora and are convinced you've got your own name wrong.
Person: "Oh, O'Hora is it?"

O'Hora: "Yes. O'HOra..not O'Hara"

Person: "Hmm, you don't hear that name everyday..."

O'Hora: "Actually I do."
O'Hora by macaluso April 23, 2009

Shannon O'Houlihan 

n. The alter ego of an Irish College student.

-A Shannon O'Houlihan usually appears when one is under the influence of alcohol.

-Once a Shannon appears he is known to make the person extremely loud, rude, and in some cases high.

-A Shannon O'Houlihan is an absolute champion of the game of Beirut (also known as Beer Pong). He has been said to quote that he "pwn3s fools" in the college sport.

-A Shannon O'Houlihan is known to enjoy many fine tasting alcoholic beverages. This includes, but is not limited to: Guiness, Smithwicks, Paps, and various Samuel Adams brews.

-A Shannon O'Houlihan can be very violent at times, use extreme caution around him.
Person 1-"Oh boy he is pretty wasted..."

Person 2-"Let's just hope he doesn't turn into a Shannon O'Houlihan."

O-holing 

The process of Briefly boiling Okra until it becomes slimy but still firm and placing it in the anus. The slime enters the bloodstream through the thin walls of the lower intestine and creates a hallucinogenic effect.

Made national attention after a small article in The Wichita Post Gazette was picked up by the Associated Press.
After O-holing all night, Jake was so buzzed he broke into his own car because he forgot where he put his keys. They were in his back pocket.
O-holing by Met Kendrick September 12, 2008

Ferdinand O'Hoolihan 

An American cult film director who has experimented with a wide selection of genres. Critically, he seems to receive much praise for his films, most notable of which include The Texas Chainsaw Massacre, Nymphoid Nurses Get Nasty, Home Alone, and No Country for Old Men.
Ferdinand O'Hoolihan is one of my all time favs.