Motherfracker Share definition Flag Used once in Battlestar Galactica on Kobol. It means "motherfucker" or "mofo", but it is more suitable for TV that your kids can watch it as well x-D Talk to me you motherfracker!!! Matherfracker?! Are you serious? You gotta be kidding me, bitch! Motherfracker by Scuz April 25, 2008 Get the Motherfracker mug.