Mario Syndrome 

When a person has to 1 UP any story you tell, no matter if it's something big, small, celebratory, or traumatic.

You know that girl, Sarah? I swear she has Mario syndrome. I can't tell her a single thing without her sharing her own experience.

Mario Syndrome by anonymous June 3, 2023

Super Mario syndrome 

When a guy feels strong romantic and intimate feelings to a girl that barely acknowledges his existence, and chases after her, much like Mario does in many of his video games for Princess Peach.

Person #1: Did you see how hard Jack's trying to get Stacy to fall for him?
Person #2: Sounds like he has severe Super Mario syndrome to me.

Super Mario syndrome by yaboisquiggly October 5, 2019

Mario brothers syndrome 

The act of making stupid mistakes over and over (usually at the same point) while trying to perform what should be a simple task. This most likely happens when doing things in a rushed manner.

Mario Brothers Syndrome:
Basically, in the original Super Mario Brothers for the Nintendo Entertainment System, trying to get through certain worlds hastily causes errors on the players part. Like hitting a turtle sideways and dying instead of jumping directly on it.

Mario brothers syndrome by Trace Faulkner October 18, 2008

Mario Party Syndrome 

What happens to the palm of your hand after playing minigames in Mario Party that involve rotating the joy stick. Symptoms include soreness in the palm and/or a red mark where the joy stick was rotated.

After playing Mari Party for several hours, Jose began to experience Mario Party syndrome on his right hand.

Mario Party Syndrome by Itsa Mea Mario January 13, 2010

"50 Turn Mario Party" Syndrome 

The tendency to get sick of an extended game or movie marathon faster than you would if you were actually doing something for its regular duration.

Most often seen when someone suggests you play a 50 turn game of Mario Party, or all the tracks in a racing game, or watch all the extended versions of the LOTR.

"I'm already sick of this LOTR marathon"

"Dude, we haven't even gotten halfway through Fellowship yet. You're definitely suffering from "50 Turn Mario Party" syndrome."

"50 Turn Mario Party" Syndrome by Anteaterking December 29, 2011

Mario Kart Syndrome

A syndrome that develops in gamers who excessively play the addicting game of Mario Kart with their friends. It's harmless, for the most part. People with this syndrome will begin to hallucinate and daydream. They will start thinking of their entire life as a cartoon-like racing game. Their minds will be haunted by the sound of the "invincible star" music. Some may even start glowing rainbows and start dancing to the music in their heads. They may act jumpy around other people, thinking that at any moment someone will shoot a red koopa shell at them. People with this syndrome also might have the strange habit of collecting banana peels instead of throwing them away after eating their bananas like normal people. When you ask them why, they will almost certainly answer, "For defense against the koopa shells!". Never be caught in a car with a person with Mario Kart Syndrome. They will almost no doubt floor the gas pedal and try to "power slide". They may even laugh like a maniac and say, "You won't beat me this time Luigi!". If you take something that belongs to a person with Mario Kart Syndrome, they'll say, "F---ing Boo stole my item again!" People with Mario Kart Syndrome might also have a strange craving for mushrooms. Lots and lots of mushrooms...

Dad: *playing Mario Kart* Oh yeah! Toad you just got SHELLED!
Daughter: Dad... please... that game's for little kids... You'll get Mario Kart Syndrome at this rate.
Dad: Pfft! That's just a myth.
--Next day--
Dad: *driving his daughter to school and starts flooring the gas pedal and power slides all over the place*
Daughter: DAD! WHAT ARE YOU DOING?!
Dad: ...must... defeat... Donkey... Kong...
Daughter: Dad...? Are you alright...? DAD?!
Dad: I'm better than alright... I'm... *the whole car starts glowing rainbows* INVINCIBLE! *takes his hands off the wheel and starts dancing to "invincible star" music that just started playing on the radio*
Daughter: wtf? *the car goes through several other vehicles unharmed, sending each car it runs through flying*
Dad: *throws banana peel out the window* TAKE THAT YOSHI!
Daughter: DAD! LOOK OUT!
Dad: Huh? *invincibility wears off and they crash into a tree*
Daughter: *looks at watch* Great... Now I'm going to be late for school! ...I hope you're happy Dad!
Dad: Aw man... *head hits steering wheel* I got eighth place!

Mario Kart Syndrome by Wiseguy16 November 27, 2012

Mario Kart Syndrome

Someone who insists they’re the best at Mario kart (despite sucking) when the popular Nintendo game is brought up in any conversation

Person 1: You wanna play Mario Kart?
Person 2: Yeah man I’m the best at Mario kart
Person 1: looks like another case of Mario Kart syndrome

Mario Kart Syndrome by keeys July 25, 2021