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hot one in the chamber 

suddenly coming to the brink of having a bowel movement with immediate urgency
I quickly ran out of the Board meeting, down the hall to the closest bathroom as I had a hot one in the chamber which couldn't be contained for a second longer.

one in the chamber

anything awaiting release; could be a terd, a rhyme in battle, something on your mate or the most popular use: a slug with a nigga's name on it
I got one in the chamber for da ass
one in the chamber by acdegrees November 12, 2004

one in the chamber

The phenomenon of a turd suddenly and forcefully entering the rectum, signaling an urgent need to expel it.
Oh, man, where's the bathroom...I got one in the chamber.

Bullet in the Chamber 

Having a discharge-able amount of feces in one's own large intestine.

The need to defecate.
" You better watch out son, I've got a bullet in the chamber"

One in the chamber

when a man has a piss and doesn't shake properly, so that when he puts his penis away he dribbles down his leg. Especially embarassing if wearing grey pants.
"Whats that on your pants, did you spill something?"
"No, I still had one in the chamber"
"oh"
One in the chamber by Paul Carey August 30, 2007

Slug in the chamber 

"Holy fuck, someone put a slug in the chamber! Smells like shit when I piss."