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High Performance Computing- Using multiple teraflop speed computers ,bound together by a MPI or PVM programming, to achieve a goal faster than one computer can itself.
IBM BlueGene/L is an example of massive scale HPC.
HPC by Xaiver July 18, 2006
Related Words
HPC HPC4L HPCA hpcc HPCD HPCL hpcwb Hottie Per Capita (HPC)
It is a crew formed by the people that hate Priscilla. HPC stands for Hate Priscilla Crew. Over 500 people have already joined HPC and they all hate Priscilla.

HPC 4 Life
Do you want to join my new crew HPC.
HPC by Robert February 27, 2004

Hottie Per Capita (HPC) 

Given the available population, how many are hotties. Also known as the Hottie quotient.
"Wow, check that out. Even the mailwoman is hot."

"Yeah, the Hottie Per Capita (HPC) is high in college towns."
A Harry Potter fanfiction pairing.
Harry Potter / Cedric Diggory.

Though the order of the initials would normally mean "A slashfiction where Harry Potter is the top and Cedric Diggory is the bottom", it is not neccessarliy true.
After reading 'Out of the Sky' on fanfiction.net, HPCD has become my OTP.
HPCD by Jessy Shaneey August 15, 2007
Acronym for "Halo PC For Life". Coined and used by remaining HaloPC and Custom Edition die-hards.
I will play HPC4L.
HPC4L by -snafu- / SiNTaXaTioN November 16, 2011
HPCS aka Hairy Plumber's Crack Syndrome.
PCS,Plumber's Crack Syndrome,Hairy,Coin Slot,Ass
Plumber's Crack full of ass hair
Dude look away that teacher has HPCS.

Holy shit HPCS ahead turn and run.
HPCS by Koga July 28, 2006