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Equis is spanish slang word used like "for reals"
Esta loca,

Equis si esta un poco locita

She's crazy
For reals she is crazy
Related Words

tres equis 

Spanish for 3 X's, also written XXX, as in the rating on pornographic movies. Derived from the Beer Dos Equis. Can be used to keep the topic of your conversation about porn a secret.
"Is there any Tres Equis on this computer?"

"Have you heard of Audrey Bitoni? She works for Tres Equis."
tres equis by Al Shermanston August 19, 2009
A girl under the age of 21 in the club. Usually given the mark of an "X" on both hands in permanent marker to signify they are not old enough to drink.
"Bro the last girl you dated was old enough to be your mom, so tonight we're gonna go out drink some beers, and get you a dos equis."

"I dont always date young girls, but when i do, i prefer dos equis"
dos equis by Jay Edward October 8, 2011
A dos equis is said to occur when two incredibly attractive women, either together or coincidentally, stand within three feet of each other, rendering any straight male within one hundred feet speechless.

XX, where each roman numeral ten represents a dime or perfect ten on the bitty scale.

Also, Dos Equis is a brand of Mexican lager.
Don't look now, Geoffrey Starkleton, but there's a dos equis right behind you!

Bernerd, you should've seen the dos equis I bedded last night, what a damn casanova I was.

Hey, Dandelion Bastardnut and Jennifilia Fluffertits, you two are a regular dos equis over there.

My dreamjob last night involved not one, but two dimes—that's a dos equis if I've ever seen one.

The last time I saw a dos equis, I exploded eight ways to Sunday, Breren Jarlz.
Dos Equis by DPaptG February 6, 2010

Bros Equis 

A term of endearment for use by LAX bros. Similar to bro or broseph. This word was formed by the ability of laxers to turn ordinary words into bro words by putting bro in it. This particular term originates from the Dos Equis guy, otherwise known as The Most Interesting Man in the World. This term generally refers to LAX gods, or those of high broly stature.
Lax bro1: "Hey Bros Equis, what are you doing tonight?"
Lax bro2: "The usual, shotgunning Nattys with my spoon and my slampiece"
Bros Equis by Lax4Lyfe August 9, 2010
When two males beat their boners on to one individuals head. Can either be a sexually pleasurable act or an act of punishment
John: Hey Tim you want a Dos Equis?

Tim: Yup

John: Alright lets do this Joe
Dos Equis by Big Red 78 March 14, 2011