D.U. 

When something really lame occurs, one may exclaim "D.U."

"D.U. Look at that drunken construction worker piss on himself."

D.U. by stink-foot January 17, 2007

D.U. 

fellatio; blow job; oral sex performed on a male; acronym for "drink up"

Male: Ayo shorty when Imma get that D.U.!
Female: You got me twisted! I don't put my mouth on nothin!
Originated at Lincoln University in Missouri

D.U. by izwhateva July 19, 2010

d'u 

short for do you.

d'u get it

d'u by Hyderite June 5, 2021

D.U.High.

Driving under the influence of the ganja.

Damn its time to go and i'm high as a georgia pine! i'm gonna get a D.U.High.

D.U.High. by M&K09 November 30, 2009

D.U.N. Dunskis 

When you have had too much to drink and pass out.

Have you seen Jarrod after all those shots?? He is D.U.N. Dunskis!!

D.U.N. Dunskis by Nooooooooooots July 27, 2019

D U T T

To wish bad on someone, instead of saying "I hope he dies" you could say "I dutt on him" or, if you're doing it for shits and giggle, you could say "I dutt on anyone named Samantha."

We D U T T on anyone named Bartholomew.

D U T T by canigetauhhhhhhhhanimetiddie December 20, 2017

D.U.O.H. 

Dried Up Old Hag

We were surprised to find out that our 35 year old co-worker was dating a D.U.O.H.

D.U.O.H. by Sharon2008 December 17, 2008