Anxed 

What a Crouching_Tiger does to deliberately annoy his fellow forumites.

C_T anxed us again with his made up words.

Anxed by BurntKitty August 3, 2010

annedamas

A shop or a word to say when there is nothing else to say

Definition 1: Let’s go to Annedamas

Definition 2: awkward silence) Boy: Annedamas

annedamas by George smithster February 10, 2019

anhedonia 

Noun. The inability to experience pleasure. adjective form: anhedonic.

I would commit suicide, but my anhedonia would prevent me from enjoying even *that*.

anhedonia by YourLordAndMaster December 23, 2003

antediluvian

before Noah's ark; the period before the flood; really really old

They argued that their equipment was antediluvian and needed replacement.

antediluvian by awesome chick12345678909876543 December 4, 2011

anxessfuselmed 

angs-ess-fyoo-zelmd adjective; an indescribable feeling that is accompanied by the emotions of anxiety, stress, confusion, and a state of being overwhelmed.

Hannah: "Man, these finals are killing me."
Devon: "Yeah, I'm feeling pretty anxessfuselmed"

anxessfuselmed by phlipfone December 4, 2016

Anhedonia 

The loss of interest and enjoyment in all activities that you once liked; the feeling of not caring anymore.

I have been feeling Anhedonia lately.

Anhedonia by cc707 January 26, 2021

anhedoniac

is one who suffers from anhedonia, the inability to derive pleasure from normal pleasurable things in life.

If someone is depressed, or has one of many different chemical imbalances in the brain.

-Comedians, for example, may be prone to having this, as what actually makes them laugh has been used so much, that that part of the brain has "worn off funny".
Funny incidents and stories are enjoyed less and less, as time goes on.
(Try telling a comedian a joke, any joke.)

A chronic masturbator has a dopamine imbalance, rendering him or her an anhedoniac, incapable of enjoying normal life in a non orgasmic state.

A person with multiple lovers/sexual partners in life cannot settle down to marry. The more they sample, the less they are able to settle, as a direct result of wanting something "strange" or "new" all the time.

Beautiful, rich people in Hollywood have, or can have anything, or everything, or almost any ONE they could ever want, anytime and all the time. Anhedonia from repeatedly fulfilling their desires is a forgone conclusion in some cases.

(In old school parlance, "too much of a good thing".)

(This may effect more people than we know as the pursuit of pleasure on this planet for it's own sake is rampant.)
e.g. "I can't WAIT for the weekend!"

anhedoniac by Omega Rat 1 August 26, 2009