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refer to single songs pressed onto a vinyl disc. The number 45 represents the rpm (revolutions per minute) that the vinyl needs to be played at, with standard size LPs requiring 33 1/3 rpm. Though they are called singles, they can hold roughly ten minutes worth of music between both sides.
Let's go back to my crib and play some 45's
45's by Derek McGregor November 8, 2019
6 up, rollin 9's, 5-0,etc.
i.e.- Watch out for the 45's
(pronounced four-fives)
45's by R U it January 19, 2006

i have 2 number 9's a number 9 large a number 6 with extra dip 2 number 45's one with cheese and a large soda

a sentence used by BIG SMOKE in the game grand theft auto san andreas
*cj ryder and sweet are looking at big smoke while he is taking his order=*

i have 2 number 9's a number 9 large a number 6 with extra dip 2 number 45's one with cheese and a large soda
D cup or larger breasts
colt 45's by Anonymous June 5, 2003

that's 45 

similar to the phrase 'keeping it 100'

meaning it's okay, no worries, etc.
I just killed your cat.

That's 45, she has 8 more lives.
that's 45 by JackJ September 16, 2013
An adaptor that allows large-hole 45 RPM records to be played on record players with a normal spindle.

A cheap, plastic gadget that snapped into the large center holes of 7-inch 45 records; unlike adaptors that were placed on the record player itself, these were meant to be installed on records, and usually left on permanently. The gadget consisted of several plastic arms radiating from a center containing the hole; the multiple arms' resemblence to spider legs is the source of the nickname "spider."
I need to get some 45 spiders for these singles, because I lost the adaptor that came with my turn table.
45 spider by SG Fan October 31, 2004