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Another name for something someone plays on guitar, generally something short, solo like, and not going anywhere particular, but it's not limited to that.
I was jamming with my Fender Telecaster, and my girl was impressed with my tweedles.

I was recording some random tweedles, and one of them ended up being the solo on the final cut.

Um, I think Mick's in his room, tweedeling about on the guitar.
Tweedles by SilentVendetta September 23, 2010
Related Words

tweetlessness 

When you can't sleep because you are trying to think of things to twitter the next day.
"Dude, you look tired..." "Yeah, I was up all night--tweetlessness..."
tweetlessness by FitzLovin' May 28, 2009
i sure do wish i could get to the pharmacy and get my tweedles for my back pain.
tweedles by frantannaman December 4, 2009
a wild variety of psilocybin mushrooms (hallucinogen)
Person1: Ay you got the hookup for the tweezes...
Person2: Yea let me get that for you.
Person1: Fasho.
tweezes by ashhleywils August 15, 2012

tweetless 

Refraining from tweeting. Finding that you have nothing to tweet or write. Drawing a blank when contemplating your Twitter page. Also used when one is stunned or surprised by something viewed on Twitter.
I'm tweetless after hearing that Aston Kutcher has stopped evangelizing Twitter.

With nothing to do but describe my latest latte buying excursion I suddenly found myself tweetless.

That boring Oprah was mercifully tweetless today.
tweetless by seacrest11 May 28, 2009

Tweetless Day 

A national holiday that occurs whenever President Donald Trump uses every last ounce of willpower to keep his tiny hands off his phone and abstain from tweeting for 24 hours.
John: The president hasn't tweeted for over a day now. I guess there's no fake news today.
Jill: Happy Tweetless Day!