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A dirty girl, also known as a hoe or even a skank.
Dude look at that skezzer on the dance floor, she would do anything.
Skezzer by cdizzle100 January 5, 2008
Related Words
skrezz skezzer skezzy skezz skezza Skreeze skrizz skrizzle Skrizzy sprezzatura

sprezzatura 

A term defined in the Renaissance that simply means doing something extremely well without showing effort. A main synonym would be "grace". It also can apply to not trying too hard to acheive something (i.e. women putting on makeup). It was popularize in Castiglione's Book of the Courtier, stating that it was a necessary trait for a perfect Courtier.
The magician showed much sprezzatura as he performed his act with ease. It is as though it comes to him naturally

the skreezies

slang term for making something from "scratch".
"Yeah, dude--I'm baking some oatmeal raisin cookies from the skreezies!"
the skreezies by mamma murder December 16, 2010
A penis which, when erect, tends to curve downward in the opposite manner of a captain hook.
Jenn was disgusted when she witnessed Andrew becoming hard while his penis curved down, forming a skezz.
Skezz by Chase Cheffe August 4, 2007

Skrizzled 

1.Out of the normal mindset, due to the aftermath of narcotics and alcohol.

2.Having just gotten a large lump sum of cash.
1. Yo bro, them 3 Jaeger Bombs, 4 Bong Hits and 666 lines got me skrizzled.

2. We robbed a bank, got skrizzled, and got a Q P.
Skrizzled by SkrizillaMyNilla January 24, 2009