Broken in a crippling sort of way. Something central to operations of the thing is severed, damaged, or impaired as to not allow it to function properly.
Man, Steve musta been surfin' for porn on my laptop yesterday because now it's totally sconzed and only boots to safe-mode.
When you drink an egregious amount of alcohol, smoke one bowl of weed and you transform into a state of temporary shaking in which you cannot control your movements or complete menial tasks.
Jimmy: Holy Sh*t! John drank so much tonight and now he’s smoking?