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sayonara motherfucker 

Something a person would say to another before he/she shoots the other person...
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Sayonara Zetsubou Sensei

Probably one of the weirdest manga ever penned by the Japanese. Written by the satirist Koji Kumeta, it tells the tale of one Kafuka Fuura, who discovers her teacher, Nozomu Itoshiki, under a sakura tree...

He is hanging by the neck in one of his many suicide attempts. She, being endlessly optimistic, thinks he is simply trying to make himself taller. Needless to say, this is where things get quite strange...and hilarious.

He teaches a class full of strangers, from the hikikomori, to a Disassociative Personality Disorder suffering transfer student, to a stalker, to a ridiculously OCD psychopath. And a normal girl.

The series does not take itself seriously at all, and is probably the darkest, strangest, and most disturbing comedies in existence.

AND I LOVE IT.
I'M IN DESPAIR! THE FACT THAT SAYONARA ZETSUBOU SENSEI HAS ENDED HAS LEFT ME IN DESPAIR! THERE'S NO HOPE! I'M GOING TO GO DIE!
a really cute and smart girl. she dresses classy and elegant, and she is just such a sweetheart.
There aint no sunshine when Saloua is gone..
Saloua by SmileEveryDay272727 March 21, 2013
the sweetest, funniest, smartest girl ever. she will make you laugh and make your whole day seem brighter and happier with just one smile. she is very loyal and will do anything to make someone feel better. she is a very busy girl who tries hard to keep up with her life and be obligated to everything. she tries her best to make room for her schedule for everyone but knows how hard it can be when there are strict rules that she must follow. she can be quite a rebel and can be real freaky when she wants to (wink wink ;))) ) If you ever fall in love with a salena, remember that she loves you and dont ever let her go even though times may get rough for both of you.
That girl looks like a Salena tbh.
salena by broskiinthebag100 October 8, 2019

Sayonara Bitches 

Phrase used to announce that you are leaving the premises like a Boss and/or Badass
Inferior Co-Worker: Are you leaving?
Superior Self: Yeah, Sayonara Bitches
Sayonara Bitches by THAT Guy June 15, 2012

Sayonara 

Japanese for 'goodbye'; however, it carries more finality. Instead of being used at the end of a day, as in "Goodbye see you tomorrow," it would be used in situations where you will either not see the person for a long time, if ever again.
Man: I'm sorry my trip is taking me overseas for an indefinate amount of time, I will call you as often as I can!

Woman: Sayonara! *tear*
Sayonara by A Man Called Michael October 15, 2009