ex. I came to work knowing good and hell well I was sick. So obviously someone was gonna get it. I "pre-apologized" to anyone who may get sick because of my ass.
The act of apologizing for anything that people will take offense to before you do it. Prepologies are often associated with high levels of alcohol and sometimes drugs.
A boyfriend's prepology: "Hey Rachel (girlfriend), I just want to prepologize for anything dumb I do tonight. (I'm really drunk.)"