A cultural term used by African Americans to describe the sleepy feeling that comes from eating too much food.
I've got the niggaitis and need to take a nap now.

Mama Duke's cooking always give niggaitis.
by Berry August 16, 2004
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A derogatory term that originated in the late 20th century used to blame ill health on black people in a racist manner
I woke up this morning suffering from a bout of niggaitis.

Doctor the back of my throat feels sore. I’m afraid you’ve contracted niggaitis. It should clear naturally with some rest
by Llcoolj-theogtriple May 27, 2018
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Having a extremley full stomach and no energy to move.
I'm so full I don't feel like doing nothing but laying here, I think I have niggaitis.
by The1nonly April 4, 2013
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The syndrome that may afflict certain people after they smoke weed. Sometimes, after smoking, one will feel tired and lazy, only wanting to sit around and do nothing. This phenomenon has been associated with the stereotypical black person, or nigga. May also be referred to in conversation as

"the itis"
Guy 1: "Dude, I'm so stoned right now. I can't even get up off my ass."
Guy 2 (to friend): "Look at him bro- niggaitis strikes again!"
by stoner44 August 4, 2009
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an infection started from the slave trade, a slave escaped and met a man where then they involved in sexual intercourse, leaving the man with a black throbbing cock which made his penis hole burn, it makes you “complete” at random times throughout the day, also leaving black bumps which turn into creatures we call “ale” which the CIA has declassified, niggaitis is a widespread disease, these “ales” have a mind of their own, growing legs, later reproducing with themselves by nutting in their own mouth, a scientist by the name of “Jose” contracted this disease he later named in niggaitis.

founded in the 1600’s niggaitis is a staple in the black homosexual community, known as the jiggaboo’s a tribe which wild spread the disease on to many men in the generation A.S.S you may be asking, how can i get rid of this disease? well the answer is simple. chop it off, chop what off? yo dick ñigga. this disease produces a disgusting smell, stinking of musk from the ballsack, pickles, cheese, honey barbecue, and cancer.
my friend is contagious, i think he has niggaitis…
by boom boom bow March 4, 2023
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