A woman/man who works behind the bar in a strip club and regularly masterbates over the strippers.
Man: I once had a girlfriend, she was a megawhore. She'd come back from work so wet, I could collect her fadge juice in a cup and use is as lube for the serious buggeration she recieved afterwards.

Woman: My husband is a megawhore, he loves his job an awful lot. God knows what he gets up to.
by PatrickWolf July 24, 2009
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A female who is not loyal to her boyfriend because she steals guys from other girls. A short and annoying inconvenience to this world.
Wow that girl Leah is such a megawhore...
but don’t even get me started on Christina.
by Gostoopidaghhh December 3, 2019
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A girl who is unfaithful, untrustworthy, and a complete waste of your time. a girl who is an easy lay, a girl who cheats, a girl who is pretty and manipulative, a girl who needs a life, and a girl recently fucked over and wants to use you as a rebound guy.
i.e. girls named megan(sometimes with bestfriends named selena, nikki, or taylor)
John:Im a virgin
Megan:We can fuck on valentines day even if i have a boyfriend...
Boyfriend:i guess you didnt change, Megawhore...
by jermface, jerm, or boyfriend February 13, 2009
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The term "megawhore" is used to describe a female who engages in sexual intimacy with a larger ration of men than your average whore. These whores are known for adding more than one body to their body count in the span of one single day. Intercourse with these women is often accompanied by the use of alcohol, narcotics, and methamphetamines. These women are suicidal to the point of weekly attempt and are failing school by thirty points or more. They have so little respect for themselves that they virtually beg for guys to spread their nudes around like a California wildfire.
Kid A: Bro I fucked _______ on saturday.
Kid B: Same.
Kid C: Same.
Kid D: Same.
Kid A: Wow she is a megawhore.
by Definitions With Class September 7, 2021
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A cell containing every STD imaginable, including both the HIV and full blown AIDS.
Husband: What caused my wife's HIV diagnosis?

Doctor: Well...um...there was a megawhore mother cell in her cervix and, um, well, uh, you guys can't have sex anymore unless you want to get The Clap.
by kopykopykopy December 23, 2011
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