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Like John Thomas, Mary Jane is a term posh people use to avoid saying vagina.
Nurse: she is ready to go to bed.
Mother: has she washed her mary-jane?
Nurse: yes her girl parts are clean.
mary-jane by EmmaJ4everxx April 22, 2018

Mary Jane 

Mary Jane is a different name for Marijuana. Also a song from Rick James which really explains it well.
Lyrics from Mary Jane sung by Rick James...

I'm in love with Mary Jane.
She's my main thing.
She makes me feel alright.
She makes my heart sing.
Mary Jane by R 2 J Through K January 8, 2005

Mary Jane 

Mary Jane is the hottest girl you will ever meet. She is very sweet and extremely lovable. shes funny and she will have the cutest laugh ever. If you meet a mary jane keep her forever and ever and ever and ever and ever and ever and ever and ever and make her your best friend or your girlfriend!
Omg that mary jane is sooo hot! i love her
Mary Jane by mzhvl; January 1, 2012

*Mary Jane

Rick James said he was in love with *Mary Jane. I think you could believe that! He wasn't the only one either.
*Mary Jane by talk2me-JCH2 September 9, 2023

Mary Jane 

Another word/phrase for marijuana, It is no particular type of marijuana, just a slang word for it in general. Also can be shortened as just Mary, not Mary Jane
I was Smokin' that Mary-Jane Yesterday.

Mary got ya paranoid.
Mary Jane by G-Fo March 3, 2005

mary jane 

Slang for marijuana. It originates from the Spanish language. Literally
Mari-Mary
Huana/Juana-Jane
"Let's smoke that bowl, hit the bong,
And then take that finger off of that hole,
Plug it, unplug it,
Don't straaaain, I love you Mary Jane,
She never complains, when I hit Mary,
With that flame, I light up the cherry,
She's so good to me, when I pack a fresh bowl I clean the
screen,"
-Cypress Hill; Hits from the Bong; Black Sunday
mary jane by azrael March 23, 2005