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Mary Jane is a different name for Marijuana. Also a song from Rick James which really explains it well.
Lyrics from Mary Jane sung by Rick James...

I'm in love with Mary Jane.
She's my main thing.
She makes me feel alright.
She makes my heart sing.
by R 2 J Through K January 08, 2005
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3
A girl named MaryJane is very cute. They are athletic, but they have a girly side too! They are easily attracted to guys. MaryJanes are usually goofy and fun, but they get distracted easily. They are usually small, but they stand their ground.
MaryJane is adorable.
by KaymoTen January 10, 2018
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4
1.Spidermans lover

2.Marijuana
1. spiderman man loves maryjane watson (the girl)

2. spiderman loves maryjane (the plant)
by SpIdUrMaN January 20, 2005
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5
Mary Jane is the hottest girl you will ever meet. She is very sweet and extremely lovable. shes funny and she will have the cutest laugh ever. If you meet a mary jane keep her forever and ever and ever and ever and ever and ever and ever and ever and make her your best friend or your girlfriend!
Omg that mary jane is sooo hot! i love her
by mzhvl; December 29, 2011
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Weed.

Just another street term, not to be confused with the candy.
Shaggy: Mary-jane's like, MY FAVORITE NAME!
by ZT May 09, 2005
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