The worst Sexually Transmitted Disease (STD) a person could ever contract. It is comprised of the following: herpes, gonorrhea, syphilis and AIDS.
"I just got back from Vegas and something really itches and burns down below!"
"Oh, I think you've picked up herpegonosyphilaids...sounds like what happened in Vegas didn't stay in Vegas!"
A combination of Herpes, gonorrhea, syphilis, and aids. Usually the first thing someone thinks of when they think about a really slutty girl/guy they don't like.
Guy - "Hey Suzy, do you know that hot chelsea chick that sits behind us in biology?"
Girl - "Yeah, she has Herpagonasyphilaids."
Guy- "No shit? So I should wear protection when I bang her?"