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A particularly nasty STD, that in later stages causes infertility, leads to your pubes falling out and eventually insanity and death. Friedrich "God is dead" Nietzsche, the German philosopher, caught this from a whore and died. Very common in the midle ages, particularly among the nobility of France. Can be covered up, externally, by a merkin. The US government conducted secret tests on African-Americans in the 30's to see how likely you were to die from syphilis. The Tuskegee Syphilis Experiments didn't end until the 1970's.

I didn't use a condom when I had sex with that whore and now I have tertiary syphilis, which is making me CRAZY! This is some bad news for my poor wang.
by me oh my December 04, 2005
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1. noun. a sexually transmitted disease that results in stinging warts, excessive stinging while urinating, and possibly bleeding from the pee hole...

2. noun. what i named my hamster in 6th grade
1. your fucking sister gave me syphilis! no wonder she was so easy!

2. rest in peace syphilis, you were so cute

remember kids, wear a condom
by wrong or right? April 12, 2007
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an STD whose origin is traced back to the vaginal tract of llamas
When the Mexican sailors became desperate, they resorted to banging llamas, hence starting the spread of syphilis.
by NikiAna May 28, 2008
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The classiest of STDs. One is said to see a bow-tie on this STD when examined under a microscope.
"That hoe is so classy she must have syphilis".
by Matt Van Natta September 15, 2010
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When a person contracts more than one case of syphilis and becomes a mutation giving them an extra head (not the regular head... you know)
When Haley got another case of syphilis from Erin she got syphili and produced a penis to go along with the vagina that was already sickened by syphilis.
by BTCHZNDHOEZ November 27, 2010
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Matt Jannsens had sex with some hog (ashley nutting) and contracted Syphilis. Word.
by xB00-RADLEYx September 22, 2009
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