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downlerium 

The perfect cocktail of depressant stimulant stabilizer and sleep deprivation which induces a state of delirium that borders on a psychotic break from reality. Basically getting so completely and totally fucked up that you don’t know your ass from a hole in the ground. A state which is near impossible to reach except by people who have a legendary tolerance for all drugs and a lifetime of hardcore habitual use that they are spoken about in hushed tones in dark back alleys and are almost mythological existences.
Holy shit man, look at that crackhead over there he’s so out of touch that he’s in a permanent state of downlerium. He ain’t never coming back.
downlerium by Guy Mandude 69 April 14, 2022

downhearted 

Utterly apathetic, as the song by Primitive Radio Gods: PhoneBooth proclaims "i've down hearted baby ever since the day we met"

totally without care, beyond depressed.
"As the prince comes to claim his kingdom, and his lover.... he finds everything is destroyed,and his lover killed, he will forever be downhearted"

downloadnet 

Networking suitable for downloading
Great songs, pics and vids can be downloaded on downloadnet.
downloadnet by Hercolena Oliver December 30, 2008

Downbear 

A Downbear is a light insult that can be used when someone does something that is mildly inconvenient
"why did you drop my pack of cards you downbear?"

Downlands College 

Can't beat toowoomba grammar in anything, bad at all sport
Him: "I go to Downlands College"
You: "fuck off"