1. A message used by the hand that is a direct insult to another person.
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1. An offensive term to tell someone to go away

Go away!!!!!!!!!!! AND LEAVE ME ALONE!!!!

"Fuck off." It's such a lovely pair of words! And it's international. I don't care where you are - if somebody's fuckin' with your bags in Lhasa Airport in Tibet and he's got a shaven head and saffron clothes on and you say "hey, fuck off!", he knows *exactly* what you mean. Exact - he will fuck off. Off he will fuck! 'Fuck off' doesn't mean 'go away.' 'Fuck off' means 'fuck... *off.*' And everybody feels what it means, nobody can write it down. There is no English equivalent for 'fuck off,' because... it *is* English, 'fuck off.' You know? And English expressions don't have English equivalents, they fuckin' *are*, ya know?

~ Billy Connoly

when someone is being bothered by another person and is starting to get really pissed off and wants them to just go away or shut up

1. (command) An exclamation of contempt with the intent of breaking rapport, usually directed towards an antagonist to go away or mind their own business.

2. (verb) To stave off responsibility or intellectual engagement, usually by spending time unproductively.

3. (noun) one who fucks off.

An exclamation of anger.