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Derealisation

A sense of detachment from reality, where surroundings appear distorted, perceptions are twisted and strangely disturbing. You may feel like you're trapped in a nightmare, enshrouded in a fog where time and space are slowed.
You know life is shite when in the grip of a derealisation episode.
Derealisation by Shougo March 24, 2022

derealization 

A feeling caused by anxiety where places that should be familiar seem 'off' in some way. Derealisation (or derealization) extremely hard to describe to someone who has never experienced it before, although if you're here I imagine you're experiencing it right now. It's often described as like a veil has been put over you that dull all your senses and your surroundings, although personally I find it's like everything is too 'vivid'. It normally goes away completely by itself when whoever experiences when they stop thinking about it. See deperonalisation
"I'm experiencing derealization, but the worst part is that I had to put the american spelling"
derealization by poopoo52 November 4, 2013

Derpamine 

The drug emitted from the brain when one is derping on addictive social media sites. The more you derp, the more derpamine is emitted to keep you derping.
While I'm trying to have a conversation with him, Jeremy keeps checking his @'s for another hit of derpamine. What a cunt.
Derpamine by Jason_Chatfield August 28, 2013

DerpAnimation

Why are you here?
Better disappear
This isn't a good site if you're under 18
Definitions all written while on caffeine
I'm not gonna lie
Gonna say it applies
I'm writing this as I sip on my diabetes
I mean Starbucks, sorry sweeties
But the point is DerpAnimation is some guy
He makes random animations on the fly
He's some stranger on the internet

He might like some things that get you upset
You don't know him and he doesn't know you
So don't search him up on Google, Bing or Yahoo
Person 1: Wow, he got attention for making trash?
Person 2: I think that's DerpAnimation
Person 1: Ah, makes sense
DerpAnimation by Derpoz March 3, 2019

desalination 

a way of turning salt water into fresh drinkable water.
e.g jack got some fresh water to drink at the desalination plant.
The female meme version of Derp or Herp. These memes are usually paired up in one set, mostly in the Rage Comics.
Herp: Look at that Derpina right there. God I had a good time with her last night.

Herp da Derp: WTF DERP THAT'S MY MOTHER FUFUFUFUFUFUFUFUFU
Derpina by lardbuster August 1, 2011