Someone who is in such a drunkenstate that they are completely and utterly delirious.
Yeah, that girl last night was so drunk she was rolling on the ground while chanting "AVADA KEDAVRA." Dude, I just sat back and watched her. Defuckinglirious, bro.
2. regaining the will or ability to think and act normally
Krystal: "Hey did you hear about Amanda & J.R.?"
Paige: "No, what happened?"
Krystal: "Amanda broke up with him & he was a really great guy!"
Paige: "Oh, don't worry...Amanda will get defuckionalized & then call J.R. back! Everything will be okay!"