Means getting intensely excited on multiple facets. Either sexually excited or any form of intense excitement.
1. Sasha started stripping and Jim exclaimed Wowzers in my trousers!
2. Justine heard she got tickets to see Maroon 5 and the prospect of her seeing Adam Levine made her say Wowzers in my trousers!
12 step recovery jargon referring to someone new who talks about how great life is, now that they'resober. Usually meaning that the person is out of touch with reality.
The new guy seems pretty happy for a dude who has no job, no money and no family. He must be on a pink cloud.