UPFA

(Pronounced oopfa) Stands for Upper Pussy Fat Area. Or the fat that hangs over a woman's vagina.

Dude, look at Mrs. Walkers UPFA!

by DustinJ March 14, 2010

upfa

Abbreviation for "Up For".
Often used when enquiring about the possiblity of sexual relations with a member of the opposite sex.

Dude: "Hey baby, upfa?"
Chick: "No"
Dude: "Bitch!"

by Bettsy September 20, 2006