sisterectomy 

The act of removing a sister from your life, either physically or metaphorically. First used in the Simpsons episode "My Sister, My Sitter".

Simpson? Look, we've already been down there tonight for a sisterectomy, a case of severe butt rot, and a leprechaun fight. How dumb do you think we are?

sisterectomy by ubersmith May 17, 2016

Sisterectomy 

The act of removing the bitch from your life cause the only time you hear from her is when she wants something!

I really need to get a "Sisterectomy" so I can have a real life!

Sisterectomy by LibertyCreekDrunkChick October 11, 2018

sisterectomy 

When a man with an African-American wife gets a divorce.

When Whitney filed for divorce, Bobby got a sisterectomy.

sisterectomy by joliet_jake1 December 9, 2008

misterectomy 

When she finally divorces the bloke. A particularly difficult divorce from a very entangled relationship. A clean surgical break from a male spouse or partner from which the prognosis for recovery is improved functioning.

Judith finally underwent that desperately needed misterectomy. Too bad her HMO won't cover it.

misterectomy by paradigmtourist May 28, 2006

fisterectomy 

Removal of part or all of the uterus through an uppercut forceful enough to render the patient permanently barren.

Chelsea wouldn't shut up, so I had to perform an emergency fisterectomy.

fisterectomy by infinityfarmer October 4, 2013

Misterectomy 

When a male has surgery that involves removing anything from the groin area.

The doctor told Dave today that a tube had developed between his colon and his bladder. Dave was shocked to hear that he needed a Misterectomy!

Misterectomy by The Baron Tube September 29, 2011

misterectomy 

Getting someone else to break up with your man for you

"Hey Todd, can you tell Brandon that I no longer want to see him?"

"So, you want to perform a misterectomy?"

"With as little pain as possible, thank you."

misterectomy by bensgirly August 22, 2011