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The act of removing a sister from your life, either physically or metaphorically. First used in the Simpsons episode "My Sister, My Sitter".
Simpson? Look, we've already been down there tonight for a sisterectomy, a case of severe butt rot, and a leprechaun fight. How dumb do you think we are?
by ubersmith May 17, 2016
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Jan 23 Word of the Day
Adjective for something that definitely wasn't lame, but not quite "hot". In other words, slightly below being hot, therefore warm, like a nice pair of mittens.
"How were things at the club last night?"

"Plenty to drink, but the music was no good. I guess shit was mittens."
by 122445 May 14, 2006
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When a man with an African-American wife gets a divorce.
When Whitney filed for divorce, Bobby got a sisterectomy.
by joliet_jake1 February 13, 2007
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The act of removing the bitch from your life cause the only time you hear from her is when she wants something!
I really need to get a "Sisterectomy" so I can have a real life!
by LibertyCreekDrunkChick October 11, 2018
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