Silenosis 

Gifted with an out of proportion enormous penis size, derived from a wood satyr companion of the God of Wine, Bacchus or Dionysus.

Luther was famed by his silenosis to inflict ambivalent orgasms.

Silenosis by Quixote March 5, 2019

Singular Sclerosis 

The retarded cousin of Multiple Sclerosis, this disease only affects male genitals, causing complete numbness, leading to permanent, untreatable erectile dysfunction.

Doctor: You've been diagnosed with Singular Sclerosis. You will never be able to pound Zucker's fat, hairy ass again.

Stelter: God dammit Donald Trump!

Singular Sclerosis by sciflyer.25 April 22, 2020

silentist

A man of reason who has dedicated his life to the pursuit of the continuing advance of human knowledge... On the most effect way to "Silence" people.

The Nazi silentists were at the cutting edge of research at Auschwitz

silentist by TheSilentist666 January 11, 2017

Silicosis 

The osu!mania player that is so good, so damn ET, he is best friends, with Etienne and looks like a Frisbee

jkzu123: Silicosis so ET he look like a frisbee, he can SS Black Stick Rot DT!
Silicosis: Not ET

Silicosis by jkzu123 (yes the real one) June 9, 2022

Vaginal Silicosis 

An irritating, disorder that can occur in both men and women. Known and diagnosable by the common person by identifying common traits such as excessive whining, complaining and generally acting as if one has sand trapped in the vagina. Those suffering ffrom this affliction tend to make others annoyed and irritated. Etiology of this disorder is unknown, though recent studies have identified "bitchyness" as a risk factor. Treatment options are limited and therapies available tend to be both painful and ineffective in long term resolution. Common name: Sandy Vagina

Her behavior might be a symptom of Vaginal Silicosis.
She's so pissed off ...she must be suffering from vaginal silicosis.

Vaginal Silicosis by Ben Sturgeon May 14, 2008

indigo sclerosis 

Indigo Sclerosis, or IS, is a short term disease that cant affect your brain, spinal cord, and the optic nerves in your eyes. It is a very rare variation of singular sclerosis. This condition is completely asymptomatic and it is particularly difficult to diagnose. Only by close inspection of the sclerosis will one find a sleight discoloration.

Sammy: Did you hear Matt was diagnosed with Indigo Sclerosis?

Mark: Yeah, he told me he was tired of explaining it to people over and over and that he wished there was more information about it available on the internet.

indigo sclerosis by Dixon_Ticonderoga January 5, 2017

Opinion Stenosis 

1. An abnormal narrowing of acceptable opinions or thoughts.

2. The process of truncating the scope of acceptable opinions in a society

Maeve was brassed off by the bigwigs' attempt to categorize her formerly nigh ubiquitous opinion that David Bowie is our lord and savior as fringe -- such irksome opinion stenosis she thought.

Opinion Stenosis by MoribundMurdoch September 16, 2020