R.O. 

Short for "Rot Off." A rot off is a member of the female persuasion who, as a result of engaging in sexual intercourse with multiple partners (males, females, animals etc.), is a host to a number of venereal diseases. The R.O. will then procede to spread the diseases, resulting in her partner's genitals rotting off.

R.O.'s include but are not limited to:
Paris Hilton
Kim Kardashian
Lindsay Lohan

R.O. by R.L. Sparkes July 24, 2009

R/O

Right On

Sam: send me that
Nick: *sends*
Sam: R/O (right on)
It’s an act of gratification or appreciation

R/O by M2S April 30, 2021

R & O

Slang for "Rude and offensive" to be used when someone does/say something mean or rude or when something occurs that one is not a fan of.

A woman tells her younger sister her ensemble is hideous. The little sister replies back saying "R & O"

R & O by dancingdoll797 October 16, 2011

R.O.U.S. 

Rodents of Unusual Size, from the 1987 movie, The Princess Bride. They are known to attack in the Fire Swamp.

-After Westley rescues her from the lightning quicksand-

Buttercup: We'll never succeed. We may as well die here.

Westley: No, no. We have already succeeded. I mean, what are the three terrors of the Fire Swamp? One, the flame spurt - no problem. There's a popping sound preceding each; we can avoid that. Two, the lightning sand, which you were clever enough to discover what that looks like, so in the future we can avoid that too.

Buttercup: Westley, what about the R.O.U.S.'s?

Westley: Rodents Of Unusual Size? I don't think they exist.

-Immediately, an R.O.U.S. attacks him-

R.O.U.S. by Kaarmu June 21, 2007

r.o.d 

ride or die, someone who you can’t life with out someone who means a lot to you, someone who can always make you smile even when you don’t think you will ever smile again. someone who is always there for you no matter the circumstances, they always have your back when none else does. A best friend that can understand you even when it is something crazy. They can joke around with you and call you names but they won’t let anyone else do it to you.

She is my R.O.D I love her so much.

r.o.d by Blah Blahhh!!! June 11, 2018

R.O.D 

Ride or Die.
Tight Friends

: Girl Your My R.O.D Chiick

R.O.D by Your Dad And Your Mum April 3, 2009

R.O.B. 

R.O.B stands for "random occurring boner"

Joe: " I got a R.O.B. while giveing an English presentation.

R.O.B. by XX_SWAGMASTER_XX December 23, 2014