Short for "Rot Off." A rot off is a member of the female persuasion who, as a result of engaging in sexual intercourse with multiple partners (males, females, animals etc.), is a host to a number of venereal diseases. The R.O. will then procede to spread the diseases, resulting in her partner's genitals rotting off.
by R.L. Sparkes July 24, 2009
Get the R.O.mug.