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Comes from the movie Scarface, where Cubans pronounce the word "man" as "mayne".
You chicken mayne...you almost made it.

Hey, hey, hey, FUCK YOU MAYNE...who put this thing together? Me, that's who.
mayne by asd September 2, 2004
Mayne: a word that is most frequently used by actor Terrance Howard
Wasup Mayne it’s me Iron Mayne.
Hey mayne you got my money mayne?

Have you heard Gucci Maynes new joint?
Mayne by My Neeg June 14, 2018
Mayne is a Southern term used the same as sayin 'man.' Its in alot of Crunk Songs.
'Yea mayne' or 'What up mayne'
mayne by Shae September 1, 2004
Word of the Day on June 8, 2006
'Mayne' is a better/ghetto term of saying man.
Examples:

One- "Mayne, she was good last night!"
Two- "Oh mayne, you nearly ran me over!"
Three- "Sup mayne?"
Mayne by Sickbitch. June 3, 2011
Regional pronunciation of the noun "man," often in the American South -- though it appears frequently in Chicago blues music, and particularly in the songs of Muddy Waters, where this pronunciation can be clearly heard.
I'm a mayne!
A full-grown mayne!
I'm a lovin' mayne!
-- Muddy Waters, "Mannish Boy"
mayne by Mel Sharkskin June 11, 2006
How people from the south say "man".
"Nah, mayne." "Wtf mayne"
Mayne by 44simtippin June 29, 2021