A pussy so nasty and filled with disease that its mear opening lets out a series of toxins so deadly it can destroy the ozone layer and be used as a weapon of mass destruction.

A local slut/whore equipped with a mass-destruction-pussy bends over slightly causeing an army of toxins to decent and every living thing within a 1000 mile radius is evaporated.

by Misty Griffith & Steph Dials March 30, 2009

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Used to describe a babe with bodacious tatas or a bangin' posterior; particularly a dime so hot that you can barely suppress the thought of using one of her boobs as a bicycle seat. Often abbreviated "HMD."

guy1: "Have you met that new girl in the office? what a babe!"
guy2: "yeah man, old news, she's a total hottie of mass destruction."
guy1: "an HMD, as it were."
guy2: "word."

by Gil Barry July 7, 2009

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weapons of mass destruction related program activities

synonym for, "We've got nothing."

"Already, the Kay Report identified dozens of weapons of mass destruction-related program activities and significant amounts of equipment that Iraq concealed from the United Nations."

by Whee February 1, 2004

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