Dufff 

To Hit somone in the head with your hand in a semi fist, using a moderate amount of force with the palm of the hand.

I dufffed him and lefta coco on his head!

Dufff by Sonny Lawrence April 20, 2006

DTFFFF 

Down To Fuck For Free Food

Adam: And all she wanted in return was free Chipotle!
Matt: Damn! She's DTFFFF!

DTFFFF by RichHomieKwon February 18, 2018

Tweedle Duffer

Someone who goes into the jungle gets bitten by a tick or denge bug and catches a 5 day fever AKA jungle fever

I held on to the antibiotics incase I met sombody who would be such a tweedle duffer as to run though the jungle with no bug spray on.

Tweedle Duffer by DemonWeapon April 14, 2017

The Duffy Effect 

When someone befriends the handicapped solely based on the fact that they have a disability. The Duffy Effect involves a person who does not take into consideration that their new handicapped friend may actually be undeserving of friendship.

Katie: "I've always been nice to Ryan, but now he asked me to prom!"

Drew: "The handicapped kid? This is a textbook example of The Duffy Effect! That kid is an asshole anyway."

The Duffy Effect by Lafferty Daniel October 2, 2008

duffle ass

A white girl with An ass so wide and out of shape that is resembles a duffle bag full of dirty laundry

Shirley over at Applebee’s is such a bitch yo!!
I wanna break my foot off in her duffle ass!!

duffle ass by Hasbeenoncewas May 29, 2018

Duffifie 

To lay a bottle on its side-after drinking its contents-to collect the few remaining drops, which can then be poured (or dribbled) into a glass. Also, to "make the bottle confess"

From Scottish (see John Jamieson's Etymological Scottish Dictionary, 1808). Now obsolete.

Grandpa Tony is always sure to duffifie after finishing his wine, proclaiming, "If it's enough to take a pill with, it's enough for me."

Duffifie by Huisman January 10, 2011

duff man 

A fictional spokesman for the beer company:
"Duff".
He represents all that is malty
and alcholic.
Tends to do alot of thrusting
to the song "Oh yeah" by Yello.

The simpsons.
"Duff man is thrusting in the direction
of the problem!"
"Duff man can never die,
only the actors who play him!"

duff man by Phoebe April 6, 2004