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ctrl+F+U 

From the web series Red vs Blue, Caboose's keyboard shortcut at command for every time he team kills.
Washington: "I told them Caboose did it. Apparently they already have a shortcut on their keyboard for recording his team kills"
Caboose: "Ctrl+F+U"
ctrl+F+U by confusedfish January 7, 2010

ctrl+shift+w 

A keyboard shortcut built into the Google Chrome browser (and some others) which, when invoked, closes all tabs in the focused window. Used to instantly erase visual evidence of objectionable activity.
I was browsing the Web for adult material when my mother walked into my room. Luckily I used ctrl+shift+w to close the incognito window I was using and she didn't suspect a thing.

Ctrl+Alt+Del 

The keys u press when ur shitty windows computer fucks up and u need to restart.
My shitty windows computer fucked up fo the 5th time in 10 min.
Ctrl+Alt+Del by cartman5000 July 26, 2004

Ctrl+Alt+Delete

A phrase that when said by a friend makes you obligated to finish your drink as fast as possible. Also used to describe someone drinking a drink super fast.
I just saw Connor Ctrl+Alt+Delete that beer so fast.

Hey bro, Ctrl+Alt+Delete
Ctrl+Alt+Delete by Cmanator April 15, 2019

ctrl+shift+n 

the reason you dont have to wipe ur history
*about to watch some thing not suppose to* "wait ctrl+shift+n"
*hides history*
ctrl+shift+n by awolfalone December 18, 2012
the button shortcut to copy something on a webpage. Also used the bug the hell out of people in chatrooms.
Ctrl+c that pic man, she's got one fine 244!
Ctrl+c by Philip George October 1, 2005