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Terrible body odour. As the late Dimebag Darrell of Pantera put it, zackleys is "when your asshole and your body smell exactly like dog shit"
"You ain't doing nothing 'til you smell like you got zackleys."

"I worked out at the gym the other day and wound up with a bad case of zackleys"
zackleys by Donno Aus. Div. November 17, 2005
Related Words
To have a perfectly sculpted body like WWE Superstar and host of Z! True Long Island Story, the WWE Internet Champion Long Island Iced Z Zack Ryder.
EVERYONE WANTS TO KNOW HOW I GET SO ZACKED, ITS CAUSE I USE THE INVISIBLE JUMPWROPE BRO! ARE YOUR SERIOUS?

BRO, I KNOW I’M ZACKED AND EVERYTHING BUT HOW DO I GET AS BIG AS YOU?

NOW I’M FEELIN SO ZACKED LIKE A Z6

AS YOU CAN SEE I’M ZACKED, BUT I’M COVERED IN HAIR
Zacked by Woo Woo Woo December 9, 2011
being really drunk and/or high
i got hella zacked last week
Zacked by rye dub January 17, 2006

Zacked out 

When your blacked out, yelling at everyone, cant walk and pissed on something in your bedroom and you only started drinking 2 hours ago
Bartender: what's wrong with your friend?
Person 1: oh he is just zacked out.
Bartender: really, I feel like he just got here. Well, I'm gonna have to cut him off
Zacked out by Dave mck October 5, 2018
A DOA word used mainly as a replacement for expressions such as, "it's all good", "I'm down with that", or "I'm good".
Person: "Hey, how are you?"
Person 2: "Zackle"
Person: "Nice."
zackle by Mike Dissinger June 22, 2006
When somebody lets out about 22 liters of silent gas from a very filthy, unwashed, shit encrusted asshole and it smells Zackley like SHIT.
As Scooby Doo and the gang had another mystery on their hands, they were cruising in The Mystery machine and all of a sudden Fred smells something coming from the way, way back and he says... "I don't know if it's you Shaggy, or you Scooby, but one of you has a serious case of The Zackleys" Scooby: "Uhhh?" Shaggy: "Zoinks , like, I don't know what The Zackleys are Fred." Fred: "Since Velma is a girl and Daphne is a girl and girls don't fart, and I can see Scooby's asshole, by the process of elimination, the person with The Case of the Zackleys is YOU SHAGGY. You farted and it smells Zackley like shit. Besides, you are such a filthy looking, grimy mother fucker, I'm sure you have a crusty asshole and you must have a load of brown foam in your under britches because I can see it running out your pant leg. Now I know why you always wear brown pants. MYSTERY SOLVED. You Shaggy, have a case of the Zackleys, you filthy mother fucker."
Zackleys by Doyle_Hargraves February 25, 2020