Those who indulge themselves with Methamphetamine until they become very paranoid and develop a seriouscase of body tremor.
eg. People who ask for money on a daily basis; people who consistently and rapidly scratch themselves. "Hey check those tweekers arguing with the cops, the one on the left looks all messed up."
eg. Tyrone Biggums from the "Chappelle Show"; Jake Mazursky from "Alpha Dog"; Every character in the movie Spun; That chick from Full House, in real life.
adv. To do things like a tweaker, or in a tweaker like manner. Most often, these things are of little significance or are tedious and unnecessary tasks.
Someone exhibiting all the telltale signs of being on tweak listed below:
1. Riding a bmx bicycle at night while being over 22 years old.(likely while wearing a pair of Dollar Tree shades)
2. Wearing a headlamp and fingerless gloves.
3. Using a Dremel rotary tool.
4. Hanging out in the auto department of walmart at 1:00am twitching around, ghost gummin’ whilst muttering random half sentences.
Hey ! Louie, wanna go to the bowling alley?!? it’s almost midnight and….AWE SHIATT!!! Louie gots the workout gloves andFaux-kley’s on!! you best leave your GT Mach 1 home bro, the cops willbust you just for lookin’ TWEAKERISH AF!!! Better leave your bag of shit with me son!!