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An extremely overly paranoid individual usuallly high on meth or some other type of stimulant...the person is usuallyvery high strung and easily distracted by most anything.
Man, stop being a tweaker andshard farming there isn't any dope in the carpet i vaccumed..
by N9NA 9MILLAMETA July 19, 2015
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Jun 24 Word of the Day
An exclamation made when your friends or family are teasing you to a point where you can't handle it anymore and a hissy fit is in order.

Derived from a YouTube user's famed outburst following Britney's lackluster performance at the 2007 VMA's.
Sarah: 'OMG Susan, I can't believe you are wearing the same skirt as yesterday. Oh, and by the way, EVERYONE knows what you did with Kevin on the weekend. Plus you look a little fat, are you retaining water?'

Susan: 'LEAVE BRITNEY ALONE!'
by Billy Chickenhole September 15, 2007
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2
A tweeker is some one who uses meth to stay up for many days.
tweaker -if you are up for 14 days you are a "two weeker".
by Lvingdedgrlinphx May 27, 2015
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3
Also: tweeker.

1. Person who constantly stays up cleaning, washing, organizing, powertooling, sorting or otherwise keeping themself busy doing menial tasks.
2. Someone who constantly makes slight alterations on (usually a very specific) object, i.e. computer, software, automobile, etc.
3. A compulsive liar, thief, or both.
4. A methamphetamine ("tweak"), or other form of speed, addict (who displays all of the above in an obsessive-compulsive manner).
"Tommy what are you doin' man?"
"I've been real busy sorting bolts!"
"For three days?"
"It's important though..."

What's the difference between a crackhead and a tweaker?
The crackhead will steal your shit and bounce--the tweaker will steal your shit and then help you look for it.
by A New STD February 12, 2005
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4
A tweaker is someone high as fuck on crystal meth. Tweakers can have sex with their partners for days at a time. They love to clean, organize, pace, etc. Tweakers can never sit still and can only focus on one thing at a time.
That tweaker has been fucking her for 10 hours straight.
by I Love Meth October 15, 2013
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5
An individual who uses methamphetamine and enjoys tinkering with clocks, cars, electronics, organizing junk or just coloring a picture. They are extremely meticulous and can be easily identified by a headlamp or flashlight which is inclusive to the tweaker culture. Can usually be found in the company of shadow folk.
The tweaker moved with ninja like percission across the parking lot of his local Walmart.
by LilBunny516 January 15, 2018
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6
People who are paranoid, delusional, uneducated, and covered with oozing chemical scabs and ulcers due to the acute abuse of methamphetamine. They eventually eat scabs from one another that contain the meth that their body can't dispose of, just to catch a cheap thrill. MMMMM....MMMMMMMMM!!!
I called the DEA the other day on those tweakers down the street.
by running out of patience December 14, 2007
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