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An extremely overly paranoid individual usuallly high on meth or some other type of stimulant...the person is usuallyvery high strung and easily distracted by most anything.
Man, stop being a tweaker andshard farming there isn't any dope in the carpet i vaccumed..
by N9NA 9MILLAMETA August 12, 2015
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Also: tweeker.

1. Person who constantly stays up cleaning, washing, organizing, powertooling, sorting or otherwise keeping themself busy doing menial tasks.
2. Someone who constantly makes slight alterations on (usually a very specific) object, i.e. computer, software, automobile, etc.
3. A compulsive liar, thief, or both.
4. A methamphetamine ("tweak"), or other form of speed, addict (who displays all of the above in an obsessive-compulsive manner).
"Tommy what are you doin' man?"
"I've been real busy sorting bolts!"
"For three days?"
"It's important though..."

What's the difference between a crackhead and a tweaker?
The crackhead will steal your shit and bounce--the tweaker will steal your shit and then help you look for it.
by A New STD February 12, 2005
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A tweeker is some one who uses meth to stay up for many days.
tweaker -if you are up for 14 days you are a "two weeker".
by Lvingdedgrlinphx May 29, 2015
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A tweaker is someone high as fuck on crystal meth. Tweakers can have sex with their partners for days at a time. They love to clean, organize, pace, etc. Tweakers can never sit still and can only focus on one thing at a time.
That tweaker has been fucking her for 10 hours straight.
by I Love Meth October 15, 2013
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People who are paranoid, delusional, uneducated, and covered with oozing chemical scabs and ulcers due to the acute abuse of methamphetamine. They eventually eat scabs from one another that contain the meth that their body can't dispose of, just to catch a cheap thrill. MMMMM....MMMMMMMMM!!!
I called the DEA the other day on those tweakers down the street.
by running out of patience December 14, 2007
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An individual who uses methamphetamine and enjoys tinkering with clocks, cars, electronics, organizing junk or just coloring a picture. They are extremely meticulous and can be easily identified by a headlamp or flashlight which is inclusive to the tweaker culture. Can usually be found in the company of shadow folk.
The tweaker moved with ninja like percission across the parking lot of his local Walmart.
by LilBunny516 January 15, 2018
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A person that is under the influence of methamphetamines and is in the middle of three projects at the same time none of which will ever be completed.
I watched Johnny search through his bag with one hand while making something with the other,he is such a tweaker.
by Jamie Pheloney April 09, 2005
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