mixcuse Share definition Flag A cross between the words "mistake" and "excuse", meaning a excuse for a mistake. Jack: Hey, man. I'm sorry I'm late.John: Don't give me any more of your mixcuses. We're late now. mixcuse by Kerouac Kat August 24, 2009 0 0 Get merch Get the mixcuse mug. Buy Now — $32.95 See more merch