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The term used by females for their male bestie. Best male friend. He is your confidant, your wing man, your partner in crime, your shoulder to cry on and there for you through thick and thin. It's only platonic, but he means the world to you and you never know what shenanigans your futures hold.
I love my Mestie. He's the best guy I ever met.

Girl, have you met Fred? He's the best guy ever. My Mestie. 💗
Mestie by Bluebird33333 September 13, 2019
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Your best male friend. Your favorite brother from another mother. Your closest guy friend, usually no hanky panky and nicest way of saying friend-zoned. Dude bff
No he’s not my boyfriend he’s my mestie .
mestie by Nature Ninja April 20, 2018
Related Words
mestie musties mestizo mastie meatie messier mester Mesticle mestiza mystie

horn mestizo 

1. a. A person of mixed European and Native American heritage or descent who rambles in his/her speech, b. eats an inordinant amount of carrots, or c. cramps the bug.

2. Harsh sun

3. Withered corn stalk
1.a) That ol' horn mestizo is really annoying, and if he don't shut his trap soon, I'm gonna lamblast the son'u'bitch
1.b) The horn mestizo over there sure can eat alotta them carrots
1.c) Check out that friggin' horn mestizo!

2. I grew increasingly hot in the horn mestizo.

3. The shanks of the horn mestizo ruffled in the rising wind.
horn mestizo by P'tainz March 25, 2011
Have fun at your meeties
meeties by mk2014 April 18, 2014
1. Originally used in Spanish to refer very specifically to a person of 50% European and 50% Amerindian descent.
2. Nowadays used to refer to any Hispanic person of mixed Amerindian and European descent, regardless of proportions. Sometimes even used as a general term for any Hispanic person of mixed racial origins.
3. Sometimes used to refer to the Hispanic culture of the Americas (as it is a mix of different indigenous, European and African cultures).

The cognate word in Portuguese is mestiço, while in French it is métis.
1. "Mestizo" was just one category in the very complex system of racial categorization used by the Spanish Empire.
2. Most people in Mexico, Central America, Ecuador, Colombia and Paraguay are mestizo, while in Chile, Argentina and Uruguay most people are just of European descent, and in Peru and Bolivia most people are Amerindians.
3. "We are one single mestizo race from Mexico to the Magellan Straits." - Ernesto "Che" Guevara
mestizo by backpacker_x2 February 21, 2011
A Spanish word literally meaning "mixed" usually refering to someone who is mixed between Spanish and Native American.
Girl: That guy is fine as hell
Friend: Yea, he's a mestizo
mestizo by COMMUNIST_USA September 18, 2005
Super kind, intelligent, and talented. Well versed in music, art, and basically everything! A great person who can brighten your day!
Meslie is lit af
Meslie by Big Dondon March 27, 2017