The term used by females for their male bestie. Best male friend. He is your confidant, your wing man, your partner in crime, your shoulder to cry on and there for you through thick and thin. It's only platonic, but he means the world to you and you never know what shenanigans your futures hold.
I love my Mestie. He's the best guy I ever met.

Girl, have you met Fred? He's the best guy ever. My Mestie. 💗
by Bluebird33333 September 13, 2019
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Mesty describes a person who is messy and nasty. Additionally it can describe someone who doesn't smell good and is musty. Individuals who go out in public without looking presentable or make a fool out of themselves in public places are mesty. it can describe a persons attire, the way they smell and their actions.
"That woman in the grocery store was so mesty with her fishnet stockings and smeared make up."

"All my husband does is look at mesty women on MySpace all day. How disgusting."
by Kimi Davis December 23, 2013
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Quite simply, the meaning of life.

Mesty originally derives from ancient scholars in Greece and Rome from the original Latin word 'Mestis'- 'mes' the Latin word for 'meaning', and 'tis' meaning 'existence' or 'life' in English. The word in modern times has been forgotten and left behind and only used by those experienced in rock music, drugs and the secret third step only known to the inner members of the Mesty Clan.
Andy: Oi Tristan.

Tristan: Yeah?

Andy: Mesty.

Tristan: Dude, are you trippin'?

Andy: Yeah man.
by Andy Quem June 11, 2007
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Your best male friend. Your favorite brother from another mother. Your closest guy friend, usually no hanky panky and nicest way of saying friend-zoned. Dude bff
No he’s not my boyfriend he’s my mestie .
by Nature Ninja November 27, 2017
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