Meffed Up 

When a methhead does something f'd up. (or messed up)

Meth-heads by nature have nil, or at best, limited teeth left.

Hence the pronunciation of "Meffed Up".

Can be used to describe a person's appearance, or an egregious situation, the term can be used quite broadly and still remain effective in meaning.

Did you see that lady back there... (grimaces/smirks) "Dude, she was all meffed up!!"

Meffed Up by NWH November 3, 2010

muffed up 

The polite way to describe somthing that is "fucked up"

Jack muffed up Jason's face after Jason attempted to finger Jacks mothers asshole while she was sleeping.

muffed up by scott January 30, 2004

muffed up 

muffed up means fucked up. use "muff" to replace fuck. very fun to use so you dont get in trouble by the parentals or offend the old folks. use different variations of muff too-muffer, muffing, etc.

That's muffed up dude!
Go muff yourself.

muffed up by Kyle Ernesti June 18, 2006

Muffed Up 

synonym for fucked up.

slang term that is often used on Call of Duty Modern Warfare 2

Alex: Dude what did Sam do?

Tyler: He cried after getting high

Alex: Thats muffed up

Muffed Up by Alex Hildenbrand May 6, 2010

Muffed up 

In a way the same as Muff diving, but all over the place.

Damn...you got all muffed up!!!!!

Muffed up by iohnoprngs March 22, 2009

Muffed up 

phrase referring to fucking up sex by not shaving your muff

We was about to hit it right, but i reached in, felt that bush and though "damn, this bitch muffed up." She knew she muffed up too.

Muffed up by Fisherella June 30, 2009

muffed-up low-bag 

"Fucked-up hoe-bag" as censored by FXM when they air 'The Descendants'

Alexandra King: "Hey, Scottie! Raina's a muffed-up low-bag and you need to stay away from her! And she's going to be a meth-head and she's gonna get used by stupid guys!"

muffed-up low-bag by Deviant and Shaven March 18, 2014