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Is a MAJOR set back in life in general. A major lose/lost.
I got caught eating beans in the cinema and everyone laugh. Definitely a major L for me.
Major L by Rice_Daddy March 21, 2020
"Well, I'm not sure if you've heard or not, but my dad passed away, so I've been dealing with that..."
"Major L"
Major L by isekai2 July 14, 2023

c major lips 

when one's lips look of josh dun's. To explain how ones lips are viewed. In account to the forest fic.
A boy with bright blue hair and mocha eyes (and C major lips and blue-sky hands and tiger-growl teeth) stands up.
c major lips by jishbuns January 23, 2017

major label

Term used in connection with any of the five record companies that dominate the music industry.

Sony, Universal, BMG, EMI and Warner (and their innumerable subsidiaries) account for over 90% of the music sold in the United States and up to 80% globally. The majors are typically characterised as greedy, cynical, bandwagon-jumping and litigious (see also RIAA).

Not all artists signing to major labels suck, but the majority do fall into one of two categories:

(1) those plucked from obscurity, who are given some songs, handed over to a stylist and aggressively marketed

(2) those with previous careers and original material, who agree to remove all traces of innovation from their music, are rejected by their old fans as sellouts and are aggressively marketed.

Regardless of their popularity, most will be financially crippled by the label's dubious accounting and will be dropped the moment sales start to falter.
"...but then they signed to a major label and were swiftly homogenised. Shame."
major label by dullthud July 17, 2003

Major League Obeseball

The so-called "professional sport" - but really just a lucrative hobby - that does not require any sort of physical fitness. Many who play are known to cheat by juicing, which leads to the ridiculous paradox of overly muscular guys covered by a layer of blubber. Often these players' heads are disproportionately big, rendering bobbleheads rather lifelike. Some defend the hobby by pointing out its cerebral strategic aspects and comparing it to chess, ignoring of course that unlike obeseball, chess players are often in decent shape and don't require other people to decide their every move.
Man I'm counting down the days to the end of Major League Obeseball so SportsCenter can concentrate on real sports.
Major League Obeseball by SHLA October 8, 2013

major league 

Slang term for something of big time, major, gigantic or huge proportions.
Hey baby, you got some major league hooters.
major league by JohnstonGuy June 30, 2005