Sertraline aka Zoloft (Sir Loft) works by increasing the levels of Serotonin a neurotransmitter in the brain. It works better controlling anxiety and panic symptoms however than depression. Side effects are more common than the literature suggests including weight gain, hair loss, decreased libido and xerostomia (whatever the fuck that is). Then there's the Sertraline Discontinuation Syndrome that includes a particularly nasty feature called brain zaps or flips, that feels like an electric shock passing through your brain.

You're still on the Sir Loft aren't you, you got those dead eyes and ashen skin.

Sir Loft by Shougo April 1, 2022

lomstead

An attractive pair of people that win at everything

You know that song "All I do is Win"? That was written about lomstead

lomstead by Taintly January 13, 2011

Concrete cowboy

A guy who thinks he's a country kinda guy, but in reality lives a comfortable city / suburban life.

Eugene: Look at that dude in the cowboy hat!
Todd: He's just a concrete cowboy.

Concrete cowboy by EugeneJohnson42000 March 16, 2024

Word of the Day on September 20, 2026

hobo loko

any hard liquor that is cheap & potent.. eg. relska, popov, potters, evan williams, kamchatka, fireball, rumpleminze, southern comfort, everclear

hey let's get a drink of that?

go ahead
*takes drink* ugh wtf is that?

everclear & bepsi
fucking hobo loko eeessshh

hobo loko by d i z k o 2 0 8 September 14, 2026

Word of the Day on September 19, 2026

God Shot

A chance happening with profound meaning, an unexpected blessing, a "sign".

Dr. Drew on Celebrity Rehab said "All of a sudden what had been just another Hollywood proposal became for him an unexpected blessing, an opportunity for growth. In drug recovery language, that's called a "God shot."

God Shot by Imogen1564 February 25, 2011

Word of the Day on September 18, 2026

city chicken

A food native to Pittsburgh/Western Pennsylvania in which cubes of pork and/or veal are put on a short, wooden skewer, breaded, then baked and/or fried.

I've heard that city chicken originated during the Great Depression, when folks didn't have enough money to buy full cuts of meat, so they assembled meat scraps on a wooden skewer, creating a make-shift drumstick. Hence the name.

Are yinz havin' city chicken for dinner?

city chicken by TRF August 31, 2006

Word of the Day on September 17, 2026

Is that cake?

Another way to say is this fake? Like the show real or cake

“Slayyyter just announced another album last night”
“No way, is that cake?”
“Yeah whoops this isn’t real”

Is that cake? by Sexyyred September 15, 2026

Word of the Day on September 16, 2026

just fokin missing her

native american reservation origin... to miss an ex so badly that everyone can see it.. can be used for either sex eg. just fokin missing her/him

friend : *noticably sad*
me : look at you all sad & shit
friend : shut up!
me : just fokin missing her huh?

just fokin missing her by d i z k o 2 0 8 September 14, 2026

Word of the Day on September 15, 2026