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it's over 

A pronouncement of the termination of a relationship by either one of the two parties involved in said relationship or an outside, objective party.
You: "Things were going so well. I called her twice a day, e-mailed and IM'ed her every five minutes, and gave up all my friends to hang out with her just to show her how much I cared. I honestly don't know what happened."

Vicfan: "It's over."
it's over by vicfan March 23, 2004

it's over 

1. your relationship
2. your dating situation
you: "i'm so confused"
shonuff: "it's over"
it's over by shonuff March 17, 2004

It’s Over 

When you become so woke that you just know it’s over.
Me: Time to go to my 9-5 today!

Eric: It’s over bro

It's over 

when its the apocalypse for you, like say you submitted something late by one minute
Dude1: Yo, did you print your English hw last night
Dude2: no dude i submitted through email, we were all supposed to
Dude1: It's over, It's all over now
It's over by TOTALLYNEVERGOOD123 September 26, 2019

It's over 

Used to repeat the fact that an incel will never get into a relationship due to unchangeable circumstances.
Truecel: I'm balding at 18 and am only 5'3".

Truecel 2: it's over for you buddy boyo.

Truecel: Never began.
It's over by its0verbuddyboyo April 13, 2023

It's over 

When something is over finished done NOT STARTING AGAIN. A relationship that has gone down the drain....
Girl to a guy: It's over
Guy to girl: What time are we going on a date
Girl to guy: What don't you get about IT'S OVER
It's over by bundlesofjoy December 5, 2011