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The chromosomes of a homosexual. Usually used to talk about a gay person.
Did you see Jerry wearing those tight pants today?

He's got some serious homosomes going today.
by Hikaru-Hikari2 November 16, 2007
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A chromosome which is genetically responsible for the homosexual tendencies of a person.
Hey Gonzales, that guy looks a bit fruity to me!
Don't be judgmental, Rastenborsky. Can't really blame the mate. He's got one too many homosomes.
by Pedro Chacha May 16, 2008
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