A variation of "Fuck My Life" used in response to hard drive, server, or other information technology failure. FSCK is a Unix command and acronym for File SystemChecK.
File System Consistency Check, or File System check is a system utility on Unix systems for checking file consistency.
Microsoft equivalents would be scandisk and chkdsk
It has been used as a profanity, as a replacement of fuck to get past autocensors/filters and also as a literal insult.
Sometimes used as general slang for to check/repair something.