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Definitely. From snoopified "for sure". Often used in preceding "my nizzle" as in "for sure, brother".
Q: "Wanna hit dis?"
A: "Fo shizle, my nizzle. Light it up!"
fo shizle by Anonymous April 2, 2003
"Are there hooker's on figueroa?"
fo shizle my nizzle.
fo shizle by darktooth211 February 11, 2003

Fo' Shizle 

"Iz u crunk?" "Fo' Sho!" -or- Fo' Shizle my Nizle
Fo' Shizle by gangstah September 14, 2006
gangsta1;yo gangsta wanna fuck my mom at the used car lot
Gangsta2; fo shizle dizle that would be off the hizle my nizle
fo shizle by nigga November 9, 2003

foshizle 

Are you going to the poop dog concert?
Ohh... ...Foshizle meing!!!
foshizle by Baddy Daddy October 16, 2003