eyehole Share definition Flag 1. (noun) An ocular orifice. 2. (verb) To gaze at or scrutinize something. 1. My eyehole is sore from wearin' them contacts! 2. I eyeholed that movie and, quite frankly, it sucked a donkey. eyehole by Amanda March 22, 2005 0 0 Get merch Get the eyehole mug. Buy Now — $32.95 See more merch